- A family of histone acetyltransferases that is structurally-related to CREB-BINDING PROTEIN and to E1A-ASSOCIATED P300 PROTEIN. They function as transcriptional coactivators by bridging between DNA-binding TRANSCRIPTION FACTORS and the basal transcription machinery. They also modify transcription factors and CHROMATIN through ACETYLATION.
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"p300-cbp transcription factors." Rhymes.net. STANDS4 LLC, 2016. Web. 29 May 2016. <http://www.rhymes.net/rhyme/p300-cbp%20transcription%20factors>.