- A family of secreted proteins found associated with the EXTRACELLULAR MATRIX and cell surface receptors. They are believed to play a role in modulating the effects of a variety of GROWTH FACTORS and PROTEASES at the cell membrane extracellular matrix. The CCN protein family is named after three protypical members; CYSTEINE-RICH PROTEIN 61; CONNECTIVE TISSUE GROWTH FACTOR; and NEPHROBLASTOMA OVEREXPRESSED PROTEIN.
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"ccn intercellular signaling proteins." Rhymes.net. STANDS4 LLC, 2015. Web. 26 Mar. 2015. <http://www.rhymes.net/rhyme/ccn intercellular signaling proteins>.